STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (872 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
     
 0.952
prpC
2-methylcitrate synthase; Belongs to the citrate synthase family.
  
  
 0.935
gltA
Citrate synthase; Belongs to the citrate synthase family.
     
 0.927
pckA
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
     
 0.919
gltB
Glutamate synthase (NADPH/NADH) large chain.
  
  
 0.904
pgk
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
  
 
 0.894
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
   
 
 0.892
pykA
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.887
GARC_2974
Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
 0.883
pycB
Pyruvate carboxylase subunit B.
     
 0.879
Your Current Organism:
Paraglaciecola arctica
NCBI taxonomy Id: 493475
Other names: Glaciecola arctica BSs20135, Glaciecola arctica str. BSs20135, Glaciecola arctica strain BSs20135, Glaciecola sp. BSs20135, P. arctica BSs20135, Paraglaciecola arctica BSs20135
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.