node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHE62786.1 | SHE87296.1 | SAMN04487965_0300 | SAMN04487965_0837 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Molecular chaperone HscC; Belongs to the heat shock protein 70 family. | 0.880 |
SHE62786.1 | SHF14867.1 | SAMN04487965_0300 | SAMN04487965_1483 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | 0.800 |
SHE62786.1 | SHF77757.1 | SAMN04487965_0300 | SAMN04487965_2677 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Type VI secretion system protein ImpD. | 0.795 |
SHE62786.1 | SHF77804.1 | SAMN04487965_0300 | SAMN04487965_2678 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Type VI secretion system protein ImpC. | 0.795 |
SHE62786.1 | SHF78221.1 | SAMN04487965_0300 | SAMN04487965_2688 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Type VI secretion system protein ImpC. | 0.944 |
SHE62786.1 | clpP | SAMN04487965_0300 | SAMN04487965_3215 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.956 |
SHE62786.1 | clpS | SAMN04487965_0300 | SAMN04487965_0301 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.987 |
SHE62786.1 | dnaK | SAMN04487965_0300 | SAMN04487965_1432 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.894 |
SHE62786.1 | grpE | SAMN04487965_0300 | SAMN04487965_1433 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.788 |
SHE62786.1 | hscA | SAMN04487965_0300 | SAMN04487965_2150 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Molecular chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.880 |
SHE87296.1 | SHE62786.1 | SAMN04487965_0837 | SAMN04487965_0300 | Molecular chaperone HscC; Belongs to the heat shock protein 70 family. | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | 0.880 |
SHE87296.1 | SHF14867.1 | SAMN04487965_0837 | SAMN04487965_1483 | Molecular chaperone HscC; Belongs to the heat shock protein 70 family. | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | 0.456 |
SHE87296.1 | clpP | SAMN04487965_0837 | SAMN04487965_3215 | Molecular chaperone HscC; Belongs to the heat shock protein 70 family. | ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.658 |
SHE87296.1 | grpE | SAMN04487965_0837 | SAMN04487965_1433 | Molecular chaperone HscC; Belongs to the heat shock protein 70 family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.988 |
SHF14867.1 | SHE62786.1 | SAMN04487965_1483 | SAMN04487965_0300 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | 0.800 |
SHF14867.1 | SHE87296.1 | SAMN04487965_1483 | SAMN04487965_0837 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone HscC; Belongs to the heat shock protein 70 family. | 0.456 |
SHF14867.1 | dnaK | SAMN04487965_1483 | SAMN04487965_1432 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.456 |
SHF14867.1 | grpE | SAMN04487965_1483 | SAMN04487965_1433 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.468 |
SHF14867.1 | hscA | SAMN04487965_1483 | SAMN04487965_2150 | HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.456 |
SHF77757.1 | SHE62786.1 | SAMN04487965_2677 | SAMN04487965_0300 | Type VI secretion system protein ImpD. | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | 0.795 |