STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHF14867.1HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. (142 aa)    
Predicted Functional Partners:
clpB
ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
 
 
 0.819
SHE62786.1
ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.
 
 
 0.800
SHF77585.1
Type VI secretion system protein VasG; Belongs to the ClpA/ClpB family.
  
 
 0.773
SHG05487.1
Molecular chaperone IbpA; Belongs to the small heat shock protein (HSP20) family.
  
  
 0.694
SHF20419.1
LuxR family transcriptional regulator, maltose regulon positive regulatory protein.
    
   0.644
htpG
Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity.
  
 
 0.638
SHF14825.1
CBS domain-containing protein.
       0.613
SHF37232.1
Curved DNA-binding protein.
  
 
 0.477
grpE
Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
  
  
 0.468
SHE87296.1
Molecular chaperone HscC; Belongs to the heat shock protein 70 family.
  
 
 0.456
Your Current Organism:
Microbulbifer donghaiensis
NCBI taxonomy Id: 494016
Other names: CGMCC 1.7063, JCM 15145, M. donghaiensis, Microbulbifer donghaiensis Wang et al. 2009, Microbulbifer sp. CN85, strain CN85
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.