STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHG25388.1tRNA-(ms[2]io[6]A)-hydroxylase. (209 aa)    
Predicted Functional Partners:
SHG18848.1
Hypothetical protein.
  
     0.707
SHE94219.1
Succinate dehydrogenase / fumarate reductase membrane anchor subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
  
     0.655
nfuA
Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
     0.602
SHF56034.1
Anti-anti-sigma factor.
  
     0.582
SHE83014.1
Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module.
  
     0.578
SHF33689.1
Hypothetical protein.
  
     0.563
SHG25425.1
Pyrroloquinoline-quinone synthase.
       0.563
SHF31528.1
ATP synthase protein I.
  
     0.557
topA
DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
     0.512
SHE94269.1
Succinate dehydrogenase subunit C.
  
     0.455
Your Current Organism:
Microbulbifer donghaiensis
NCBI taxonomy Id: 494016
Other names: CGMCC 1.7063, JCM 15145, M. donghaiensis, Microbulbifer donghaiensis Wang et al. 2009, Microbulbifer sp. CN85, strain CN85
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