STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
4CL1_14-coumarate--coa ligase 1. (134 aa)    
Predicted Functional Partners:
A4A49_10843
Putative acyl-activating enzyme 19.
  
 0.752
MED14
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.574
NUP205
Nuclear pore complex protein nup205.
   
 0.550
CYC07_0
40S ribosomal protein S3a; Belongs to the eukaryotic ribosomal protein eS1 family.
    
 
 0.547
NUP93A
Nuclear pore protein.
   
 0.543
NUP155
Nuclear pore complex protein nup155.
   
 0.542
MED31
Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
  0.535
CS
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.523
CSY2
Citrate synthase.
  
 
 0.523
NUP54
Nuclear pore complex protein nup54.
    
 0.516
Your Current Organism:
Nicotiana attenuata
NCBI taxonomy Id: 49451
Other names: N. attenuata, Nicotiana attenuata Torr. ex S.Watson
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.