STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NCS1Purine-uracil permease ncs1. (579 aa)    
Predicted Functional Partners:
PYD2_1
Dihydropyrimidinase.
 
  
 0.780
PYD2_0
Dihydropyrimidinase.
 
  
 0.778
TTL_1
Uric acid degradation bifunctional protein ttl.
 
   
 0.701
URIC1
Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family.
  
  
 0.699
NAT3
Nucleobase-ascorbate transporter 3.
  
  
 0.636
NAT12
Nucleobase-ascorbate transporter 12.
  
  
 0.636
PYR5-6
Uridine 5'-monophosphate synthase.
    
 
 0.582
THI1
Thiamine thiazole synthase, chloroplastic; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; B [...]
      
 0.581
A4A49_41838
Uncharacterized protein.
  
  
 0.579
NAT1
Nucleobase-ascorbate transporter 1.
  
  
 0.579
Your Current Organism:
Nicotiana attenuata
NCBI taxonomy Id: 49451
Other names: N. attenuata, Nicotiana attenuata Torr. ex S.Watson
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