STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OGG1N-glycosylasedna lyase ogg1. (392 aa)    
Predicted Functional Partners:
APE1L
DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.
  
 0.782
ARP
DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.
  
 0.761
APE2
Dna-(Apurinic or apyrimidinic site) lyase 2.
  
 0.750
XRCC1
Dna-repair protein xrcc1.
   
 
 0.615
POLH_2
Dna polymerase eta.
  
 
 0.614
POLH_1
Dna polymerase eta.
  
 
 0.614
FEN1-A
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 
 0.611
BHLH140_1
Transcription factor bhlh140.
    
 
 0.598
BHLH140_0
Transcription factor bhlh140.
    
 
 0.598
MYH
Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.
  
  
 0.595
Your Current Organism:
Nicotiana attenuata
NCBI taxonomy Id: 49451
Other names: N. attenuata, Nicotiana attenuata Torr. ex S.Watson
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.