Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDC2_0Cell division control protein 2-like protein. (823 aa)    
Predicted Functional Partners:
A4A49_37022
Uncharacterized protein.
   
 
 0.994
KIN7O_3
Kinesin-like protein kin-7o.
   
 
 0.993
MAD2
Mitotic spindle checkpoint protein mad2.
   
 
 0.990
BUB1
Mitotic checkpoint serinethreonine-protein kinase bub1.
   
 
 0.974
BUBR1_0
Mitotic spindle checkpoint protein bubr1.
   
 
 0.974
BUBR1_1
Mitotic spindle checkpoint protein bubr1.
   
 
 0.968
MAD1
Mitotic spindle checkpoint protein mad1.
    
 
 0.955
ESP1
Separase.
   
 
 0.946
A4A49_30355
Uncharacterized protein.
   
 
 0.943
A4A49_02787
Uncharacterized protein.
   
 
 0.943
Your Current Organism:
Nicotiana attenuata
NCBI taxonomy Id: 49451
Other names: N. attenuata, Nicotiana attenuata Torr. ex S.Watson
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