STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNEA_C_2Putative aminopyrimidine aminohydrolase, mitochondrial. (558 aa)    
Predicted Functional Partners:
THIC
Phosphomethylpyrimidine synthase, chloroplastic.
  
 
 0.963
A4A49_03372
Uncharacterized protein.
    
 0.957
TPK2_0
Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family.
    
 0.940
A4A49_27497
Uncharacterized protein.
     
 0.912
TH1_1
Thiamine biosynthetic bifunctional enzyme th1, chloroplastic.
 
   
  0.905
TNEA_C_1
Putative aminopyrimidine aminohydrolase, mitochondrial.
  
  
 
0.902
TNEA_C_3
Putative aminopyrimidine aminohydrolase, mitochondrial.
  
  
 
0.901
TENA_E_0
Putative bifunctional tena-e protein.
     
  0.900
TENA_E_1
Putative bifunctional tena-e protein.
     
  0.900
THI1
Thiamine thiazole synthase, chloroplastic; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; B [...]
  
  
 0.797
Your Current Organism:
Nicotiana attenuata
NCBI taxonomy Id: 49451
Other names: N. attenuata, Nicotiana attenuata Torr. ex S.Watson
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