CWC26 protein (Yarrowia lipolytica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CWC26

Pre-mRNA-splicing factor CWC26; Involved in pre-mRNA splicing. (221 aa)

Predicted Functional Partners:

YALI0_C16368g

0.998

YALI0_D07348g

0.995

CEF1

0.993

YALI0_F20724g

0.990

YALI0_C03982g

0.990

CWC2

0.989

YALI0_D06567g

0.985

YALI0_D27346g

0.972

YALI0_D05577g

0.970

YALI0_C19404g

0.960

Your Current Organism:

Yarrowia lipolytica

NCBI taxonomy Id: 284591
Other names: Y. lipolytica CLIB122, Yarrowia lipolytica CLIB122

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CEF1	CWC2	Q6C8F5	Q6C007	Pre-mRNA-splicing factor CEF1; Involved in pre-mRNA splicing and cell cycle control.	Pre-mRNA-splicing factor CWC2; Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic [...]	0.995
CEF1	CWC26	Q6C8F5	Q6CAX1	Pre-mRNA-splicing factor CEF1; Involved in pre-mRNA splicing and cell cycle control.	Pre-mRNA-splicing factor CWC26; Involved in pre-mRNA splicing.	0.993
CEF1	YALI0_C03982g	Q6C8F5	Q6CD42	Pre-mRNA-splicing factor CEF1; Involved in pre-mRNA splicing and cell cycle control.	YALI0C03982p.	0.999
CEF1	YALI0_C16368g	Q6C8F5	Q6CBR2	Pre-mRNA-splicing factor CEF1; Involved in pre-mRNA splicing and cell cycle control.	YALI0C16368p.	0.990
CEF1	YALI0_C19404g	Q6C8F5	Q6CBF0	Pre-mRNA-splicing factor CEF1; Involved in pre-mRNA splicing and cell cycle control.	YALI0C19404p.	0.983
CEF1	YALI0_D05577g	Q6C8F5	Q6CA63	Pre-mRNA-splicing factor CEF1; Involved in pre-mRNA splicing and cell cycle control.	YALI0D05577p.	0.994
CEF1	YALI0_D06567g	Q6C8F5	Q6CA21	Pre-mRNA-splicing factor CEF1; Involved in pre-mRNA splicing and cell cycle control.	YALI0D06567p.	0.876
CEF1	YALI0_D07348g	Q6C8F5	Q6C9Y5	Pre-mRNA-splicing factor CEF1; Involved in pre-mRNA splicing and cell cycle control.	YALI0D07348p.	0.893
CEF1	YALI0_D27346g	Q6C8F5	Q6C7K4	Pre-mRNA-splicing factor CEF1; Involved in pre-mRNA splicing and cell cycle control.	YALI0D27346p.	0.997
CEF1	YALI0_F20724g	Q6C8F5	Q6C0Y6	Pre-mRNA-splicing factor CEF1; Involved in pre-mRNA splicing and cell cycle control.	YALI0F20724p.	0.992
CWC2	CEF1	Q6C007	Q6C8F5	Pre-mRNA-splicing factor CWC2; Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic [...]	Pre-mRNA-splicing factor CEF1; Involved in pre-mRNA splicing and cell cycle control.	0.995
CWC2	CWC26	Q6C007	Q6CAX1	Pre-mRNA-splicing factor CWC2; Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic [...]	Pre-mRNA-splicing factor CWC26; Involved in pre-mRNA splicing.	0.989
CWC2	YALI0_C03982g	Q6C007	Q6CD42	Pre-mRNA-splicing factor CWC2; Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic [...]	YALI0C03982p.	0.995
CWC2	YALI0_C16368g	Q6C007	Q6CBR2	Pre-mRNA-splicing factor CWC2; Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic [...]	YALI0C16368p.	0.976
CWC2	YALI0_C19404g	Q6C007	Q6CBF0	Pre-mRNA-splicing factor CWC2; Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic [...]	YALI0C19404p.	0.968
CWC2	YALI0_D05577g	Q6C007	Q6CA63	Pre-mRNA-splicing factor CWC2; Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic [...]	YALI0D05577p.	0.869
CWC2	YALI0_D06567g	Q6C007	Q6CA21	Pre-mRNA-splicing factor CWC2; Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic [...]	YALI0D06567p.	0.960
CWC2	YALI0_D07348g	Q6C007	Q6C9Y5	Pre-mRNA-splicing factor CWC2; Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic [...]	YALI0D07348p.	0.454
CWC2	YALI0_D27346g	Q6C007	Q6C7K4	Pre-mRNA-splicing factor CWC2; Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic [...]	YALI0D27346p.	0.993
CWC2	YALI0_F20724g	Q6C007	Q6C0Y6	Pre-mRNA-splicing factor CWC2; Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic [...]	YALI0F20724p.	0.987