STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRS4Increased rDNA silencing protein 4; Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in rDNA silencing (By similarity). (1005 aa)    
Predicted Functional Partners:
YALI0_E18986g
YALI0E18986p.
    
 0.573
YALI0_A17127g
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
   
 0.560
YALI0_E29557g
YALI0E29557p.
   
 0.527
YALI0_D26015g
Serine/threonine-protein kinase.
   
 0.520
YALI0_D26510g
YALI0D26510p.
   
 0.519
YALI0_D13442g
YALI0D13442p.
   
 0.519
YALI0_B04246g
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.517
YALI0_E33253g
Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.
    
 0.513
YALI0_C12474g
YALI0C12474p; Belongs to the adaptor complexes medium subunit family.
    
 0.495
YALI0_B22110g
YALI0B22110p.
    
 0.484
Your Current Organism:
Yarrowia lipolytica
NCBI taxonomy Id: 284591
Other names: Y. lipolytica CLIB122, Yarrowia lipolytica CLIB122
Server load: low (16%) [HD]