STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lutA_2Lactate utilization protein A. (574 aa)    
Predicted Functional Partners:
nadB
L-aspartate oxidase.
 
 
 0.998
sucD_1
succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
  
 0.991
ttdA_1
L(+)-tartrate dehydratase subunit alpha.
    
 0.986
ttdA_2
L(+)-tartrate dehydratase subunit alpha.
    
 0.986
sucC
succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 
 0.983
ttdB_1
L(+)-tartrate dehydratase subunit beta.
    
 0.977
ttdB_2
L(+)-tartrate dehydratase subunit beta.
    
 0.977
lutB
Lactate utilization protein B.
0.965
KZX12151.1
Putative tRNA/rRNA methyltransferase.
  
    0.939
KZX11028.1
Methyl-viologen-reducing hydrogenase, delta subunit.
 
  
 0.830
Your Current Organism:
Methanobrevibacter curvatus
NCBI taxonomy Id: 49547
Other names: DSM 11111, M. curvatus, strain RFM-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.