STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LAFE_0B04302GD-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (470 aa)    
Predicted Functional Partners:
LAFE_0C07888G
Phosphoserine aminotransferase.
  
 0.989
LAFE_0D03576G
Tryptophan synthase.
  
 0.960
LAFE_0B08922G
LAFE_0B08922g1_1.
  
 
 0.909
LAFE_0A07712G
LAFE_0A07712g1_1.
  
 0.902
LAFE_0A02630G
LAFE_0A02630g1_1.
  
 
 0.899
LAFE_0H00584G
LAFE_0H00584g1_1.
  
 
 0.899
LAFE_0D03224G
3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
 
 0.876
LAFE_0H15280G
LAFE_0H15280g1_1.
    
 0.869
LAFE_0F09978G
LAFE_0F09978g1_1.
  
 
 0.842
LAFE_0G01398G
Histidine biosynthesis trifunctional protein.
  
  
 0.841
Your Current Organism:
Lachancea fermentati
NCBI taxonomy Id: 4955
Other names: ATCC 58446, CBS 707, CCRC 21760, CCRC:21760, CECT 11056, DBVPG 6297, IFO 0479, L. fermentati, Zygosaccharomyces fermentati
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