STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LAFE_0H07778GLAFE_0H07778g1_1. (412 aa)    
Predicted Functional Partners:
LAFE_0A01464G
LAFE_0A01464g1_1.
    
0.847
LAFE_0F16600G
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
   
 0.748
LAFE_0B02652G
LAFE_0B02652g1_1.
     
 0.714
LAFE_0E13564G
Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.
    
 0.629
LAFE_0G16292G
AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
   
 0.620
LAFE_0F16270G
LAFE_0F16270g1_1.
   
 
 0.559
LAFE_0H01354G
LAFE_0H01354g1_1.
   
 0.553
LAFE_0C02608G
Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.
    
 0.551
LAFE_0B09736G
AP-1 complex subunit gamma.
   
 0.546
LAFE_0G06326G
LAFE_0G06326g1_1; Belongs to the adaptor complexes medium subunit family.
    
 0.524
Your Current Organism:
Lachancea fermentati
NCBI taxonomy Id: 4955
Other names: ATCC 58446, CBS 707, CCRC 21760, CCRC:21760, CECT 11056, DBVPG 6297, IFO 0479, L. fermentati, Zygosaccharomyces fermentati
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.