STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LAFE_0H09538GLAFE_0H09538g1_1; Belongs to the actin family. (418 aa)    
Predicted Functional Partners:
LAFE_0F15412G
LAFE_0F15412g1_1.
   
 
 0.990
LAFE_0H06282G
RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
    
 
 0.985
LAFE_0D07536G
LAFE_0D07536g1_1.
    
 
 0.984
LAFE_0C03532G
RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
    
 
 0.977
LAFE_0E02190G
LAFE_0E02190g1_1.
    
 
 0.888
LAFE_0E01376G
Histone H2A; Belongs to the histone H2A family.
   
 
 0.877
LAFE_0D02476G
LAFE_0D02476g1_1.
    
 
 0.799
LAFE_0F06414G
LAFE_0F06414g1_1.
   
 
 0.727
LAFE_0C09098G
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
   0.711
LAFE_0C09406G
Histone H2B; Belongs to the histone H2B family.
   
   0.648
Your Current Organism:
Lachancea fermentati
NCBI taxonomy Id: 4955
Other names: ATCC 58446, CBS 707, CCRC 21760, CCRC:21760, CECT 11056, DBVPG 6297, IFO 0479, L. fermentati, Zygosaccharomyces fermentati
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.