STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDY20823.1Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (791 aa)    
Predicted Functional Partners:
EDY16878.1
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
 
 0.999
EDY20822.1
KEGG: cvi:CV_2287 ribonucleotide-diphosphate reductase subunit alpha.
 
 0.998
EDY21411.1
PFAM: protein of unknown function DUF179; KEGG: sru:SRU_0495 hypothetical protein; Belongs to the UPF0301 (AlgH) family.
   
 0.982
EDY20878.1
KEGG: hch:HCH_00685 hypothetical protein.
  
 0.907
EDY19286.1
PFAM: glutaredoxin; KEGG: cth:Cthe_0235 glutaredoxin-like protein, YruB-family.
  
 0.907
EDY19202.1
PFAM: glutaredoxin; KEGG: tte:TTE2675 glutaredoxin and related proteins.
  
 0.907
EDY19873.1
PFAM: nucleoside diphosphate kinase; KEGG: bba:Bd3827 hypothetical protein.
     
 0.890
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
     
 0.876
dcd
Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.
    
 0.866
queE
Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
  
 
 0.846
Your Current Organism:
Chthoniobacter flavus
NCBI taxonomy Id: 497964
Other names: C. flavus Ellin428, Chthoniobacter flavus Ellin428, Chthoniobacter flavus str. Ellin428, Chthoniobacter flavus strain Ellin428, bacterium Ellin428
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.