node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDY18205.1 | EDY19341.1 | CfE428DRAFT_4341 | CfE428DRAFT_3026 | PFAM: ADP-ribosylation/Crystallin J1; KEGG: net:Neut_2145 ADP-ribosylation/crystallin J1. | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: nve:NEMVE_v1g178601 predicted protein Pfam: Methyltransf_12 Methyltransf_11 PROSITE: NLS_BP. | 0.718 |
EDY18992.1 | EDY19340.1 | CfE428DRAFT_3650 | CfE428DRAFT_3025 | PFAM: cyclic nucleotide-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: afw:Anae109_3313 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | PFAM: thiopurine S-methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: gvi:gll0818 similar to thiol methyltransferase. | 0.569 |
EDY18992.1 | EDY19341.1 | CfE428DRAFT_3650 | CfE428DRAFT_3026 | PFAM: cyclic nucleotide-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: afw:Anae109_3313 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: nve:NEMVE_v1g178601 predicted protein Pfam: Methyltransf_12 Methyltransf_11 PROSITE: NLS_BP. | 0.569 |
EDY18992.1 | gcvP | CfE428DRAFT_3650 | CfE428DRAFT_3024 | PFAM: cyclic nucleotide-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: afw:Anae109_3313 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.792 |
EDY18992.1 | glyA | CfE428DRAFT_3650 | CfE428DRAFT_3607 | PFAM: cyclic nucleotide-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: afw:Anae109_3313 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.649 |
EDY19340.1 | EDY18992.1 | CfE428DRAFT_3025 | CfE428DRAFT_3650 | PFAM: thiopurine S-methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: gvi:gll0818 similar to thiol methyltransferase. | PFAM: cyclic nucleotide-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: afw:Anae109_3313 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | 0.569 |
EDY19340.1 | EDY19341.1 | CfE428DRAFT_3025 | CfE428DRAFT_3026 | PFAM: thiopurine S-methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: gvi:gll0818 similar to thiol methyltransferase. | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: nve:NEMVE_v1g178601 predicted protein Pfam: Methyltransf_12 Methyltransf_11 PROSITE: NLS_BP. | 0.783 |
EDY19340.1 | EDY19342.1 | CfE428DRAFT_3025 | CfE428DRAFT_3027 | PFAM: thiopurine S-methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: gvi:gll0818 similar to thiol methyltransferase. | Hypothetical protein. | 0.557 |
EDY19340.1 | EDY20163.1 | CfE428DRAFT_3025 | CfE428DRAFT_2087 | PFAM: thiopurine S-methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: gvi:gll0818 similar to thiol methyltransferase. | PFAM: regulatory protein ArsR; transcriptional regulator TrmB; UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: sus:Acid_5272 transcriptional regulator, ArsR family. | 0.481 |
EDY19340.1 | cysC | CfE428DRAFT_3025 | CfE428DRAFT_4547 | PFAM: thiopurine S-methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: gvi:gll0818 similar to thiol methyltransferase. | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.747 |
EDY19340.1 | gcvP | CfE428DRAFT_3025 | CfE428DRAFT_3024 | PFAM: thiopurine S-methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: gvi:gll0818 similar to thiol methyltransferase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.851 |
EDY19340.1 | glyA | CfE428DRAFT_3025 | CfE428DRAFT_3607 | PFAM: thiopurine S-methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: gvi:gll0818 similar to thiol methyltransferase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.496 |
EDY19341.1 | EDY18205.1 | CfE428DRAFT_3026 | CfE428DRAFT_4341 | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: nve:NEMVE_v1g178601 predicted protein Pfam: Methyltransf_12 Methyltransf_11 PROSITE: NLS_BP. | PFAM: ADP-ribosylation/Crystallin J1; KEGG: net:Neut_2145 ADP-ribosylation/crystallin J1. | 0.718 |
EDY19341.1 | EDY18992.1 | CfE428DRAFT_3026 | CfE428DRAFT_3650 | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: nve:NEMVE_v1g178601 predicted protein Pfam: Methyltransf_12 Methyltransf_11 PROSITE: NLS_BP. | PFAM: cyclic nucleotide-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: afw:Anae109_3313 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase. | 0.569 |
EDY19341.1 | EDY19340.1 | CfE428DRAFT_3026 | CfE428DRAFT_3025 | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: nve:NEMVE_v1g178601 predicted protein Pfam: Methyltransf_12 Methyltransf_11 PROSITE: NLS_BP. | PFAM: thiopurine S-methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: gvi:gll0818 similar to thiol methyltransferase. | 0.783 |
EDY19341.1 | EDY19342.1 | CfE428DRAFT_3026 | CfE428DRAFT_3027 | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: nve:NEMVE_v1g178601 predicted protein Pfam: Methyltransf_12 Methyltransf_11 PROSITE: NLS_BP. | Hypothetical protein. | 0.572 |
EDY19341.1 | EDY19343.1 | CfE428DRAFT_3026 | CfE428DRAFT_3028 | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: nve:NEMVE_v1g178601 predicted protein Pfam: Methyltransf_12 Methyltransf_11 PROSITE: NLS_BP. | KEGG: pcu:pc0506 hypothetical protein. | 0.657 |
EDY19341.1 | EDY20163.1 | CfE428DRAFT_3026 | CfE428DRAFT_2087 | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: nve:NEMVE_v1g178601 predicted protein Pfam: Methyltransf_12 Methyltransf_11 PROSITE: NLS_BP. | PFAM: regulatory protein ArsR; transcriptional regulator TrmB; UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: sus:Acid_5272 transcriptional regulator, ArsR family. | 0.481 |
EDY19341.1 | EDY22165.1 | CfE428DRAFT_3026 | CfE428DRAFT_0290 | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: nve:NEMVE_v1g178601 predicted protein Pfam: Methyltransf_12 Methyltransf_11 PROSITE: NLS_BP. | Chromosome segregation ATPase-like protein; KEGG: lma:LmjF34.0690 hypothetical protein, conserved. | 0.498 |
EDY19341.1 | cysC | CfE428DRAFT_3026 | CfE428DRAFT_4547 | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: nve:NEMVE_v1g178601 predicted protein Pfam: Methyltransf_12 Methyltransf_11 PROSITE: NLS_BP. | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.747 |