STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDY17728.1HhH-GPD family protein; Adenine glycosylase active on G-A mispairs. (341 aa)    
Predicted Functional Partners:
EDY17162.1
KEGG: mmz:MmarC7_0254 exodeoxyribonuclease III Xth; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase.
    
 0.941
EDY19336.1
PFAM: NUDIX hydrolase; KEGG: pai:PAE2253 MutT/NUDIX family protein.
 
 0.882
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
 
0.665
EDY17727.1
Ribonuclease HIII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
     
 0.647
EDY19992.1
KEGG: aeh:Mlg_2357 coproporphyrinogen III oxidase, anaerobic; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB.
  
    0.443
EDY19700.1
KEGG: sus:Acid_0536 DNA-3-methyladenine glycosylase I; TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase.
    
 0.442
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.439
EDY17726.1
PFAM: histone family protein DNA-binding protein; KEGG: pcu:pc1168 putative integration host factor; Belongs to the bacterial histone-like protein family.
       0.427
EDY20366.1
KEGG: abo:ABO_0002 DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III beta chain.
    
 
 0.410
EDY20367.1
PFAM: DNA polymerase III beta chain; KEGG: gur:Gura_0002 DNA polymerase III, beta subunit.
    
 
 0.410
Your Current Organism:
Chthoniobacter flavus
NCBI taxonomy Id: 497964
Other names: C. flavus Ellin428, Chthoniobacter flavus Ellin428, Chthoniobacter flavus str. Ellin428, Chthoniobacter flavus strain Ellin428, bacterium Ellin428
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