STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rtcBPFAM: protein of unknown function UPF0027; KEGG: rba:RB9360 hypothetical protein; Belongs to the RtcB family. (504 aa)    
Predicted Functional Partners:
rtcA
RNA 3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
 
  
 0.942
EDY17195.1
PFAM: sigma-54 factor interaction domain-containing protein; regulator of RNA terminal phosphate cyclase; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: mxa:MXAN_4983 sigma-54 dependent transcriptional regulator RtcR.
 
   
 0.608
EDY17196.1
PFAM: TROVE domain protein; KEGG: hch:HCH_01566 probable RNA-binding protein containing TROVE domain.
 
     0.540
EDY18130.1
KEGG: rba:RB11055 hypothetical protein.
  
     0.503
EDY18856.1
PFAM: Kelch repeat-containing protein; KEGG: rba:RB3349 conserved hypothetical protein-putative sodium:solute symporter.
  
     0.450
Your Current Organism:
Chthoniobacter flavus
NCBI taxonomy Id: 497964
Other names: C. flavus Ellin428, Chthoniobacter flavus Ellin428, Chthoniobacter flavus str. Ellin428, Chthoniobacter flavus strain Ellin428, bacterium Ellin428
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