STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDY17106.1PFAM: heat shock protein DnaJ domain protein; KEGG: rme:Rmet_1823 heat shock protein DnaJ-like protein. (338 aa)    
Predicted Functional Partners:
EDY22239.1
PFAM: phosphopantetheine-binding; KEGG: mxa:MXAN_4528 polyketide synthase.
  
 
 0.992
EDY22216.1
2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: cac:CAC0472 DnaK protein (heat shock protein), HSP70/DnaK family.
  
  0.919
EDY18823.1
2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: rxy:Rxyl_0784 chaperone DnaK.
  
  0.919
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
  0.914
EDY22217.1
KEGG: bca:BCE_1142 DnaK protein, truncation.
  
  0.908
EDY20132.1
2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: fre:Franean1_3632 2-alkenal reductase.
  
  0.874
EDY17965.1
SMART: WD-40 repeat protein; KEGG: rrs:RoseRS_4025 NB-ARC domain protein.
   
 0.823
EDY19317.1
PFAM: Immunoglobulin I-set domain protein; SMART: Immunoglobulin subtype; KEGG: gur:Gura_0373 alpha-tubulin suppressor and related RCC1 domain-containing protein-like protein.
   
 
 0.818
EDY16129.1
KEGG: fjo:Fjoh_0370 ribosomal protein L17.
  
   0.809
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
 
 
 0.806
Your Current Organism:
Chthoniobacter flavus
NCBI taxonomy Id: 497964
Other names: C. flavus Ellin428, Chthoniobacter flavus Ellin428, Chthoniobacter flavus str. Ellin428, Chthoniobacter flavus strain Ellin428, bacterium Ellin428
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.