node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADN12189.1 | ADN16288.1 | Cyan7822_0138 | Cyan7822_4374 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | KEGG: cyh:Cyan8802_3186 peptidylprolyl isomerase; PFAM: peptidylprolyl isomerase FKBP-type. | 0.431 |
ADN12189.1 | guaA | Cyan7822_0138 | Cyan7822_3098 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.485 |
ADN12189.1 | queA | Cyan7822_0138 | Cyan7822_4147 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | S-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.548 |
ADN12189.1 | ribBA | Cyan7822_0138 | Cyan7822_5568 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.742 |
ADN12189.1 | tgt | Cyan7822_0138 | Cyan7822_0782 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] | 0.465 |
ADN12189.1 | truB | Cyan7822_0138 | Cyan7822_2658 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.919 |
ADN12807.1 | ADN12809.1 | Cyan7822_0781 | Cyan7822_0783 | KEGG: cyh:Cyan8802_1195 hypothetical protein. | KEGG: mar:MAE_11230 hypothetical protein. | 0.526 |
ADN12807.1 | cobS | Cyan7822_0781 | Cyan7822_0780 | KEGG: cyh:Cyan8802_1195 hypothetical protein. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.567 |
ADN12807.1 | tgt | Cyan7822_0781 | Cyan7822_0782 | KEGG: cyh:Cyan8802_1195 hypothetical protein. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] | 0.605 |
ADN12809.1 | ADN12807.1 | Cyan7822_0783 | Cyan7822_0781 | KEGG: mar:MAE_11230 hypothetical protein. | KEGG: cyh:Cyan8802_1195 hypothetical protein. | 0.526 |
ADN12809.1 | tgt | Cyan7822_0783 | Cyan7822_0782 | KEGG: mar:MAE_11230 hypothetical protein. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] | 0.445 |
ADN16288.1 | ADN12189.1 | Cyan7822_4374 | Cyan7822_0138 | KEGG: cyh:Cyan8802_3186 peptidylprolyl isomerase; PFAM: peptidylprolyl isomerase FKBP-type. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.431 |
ADN16288.1 | tgt | Cyan7822_4374 | Cyan7822_0782 | KEGG: cyh:Cyan8802_3186 peptidylprolyl isomerase; PFAM: peptidylprolyl isomerase FKBP-type. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] | 0.535 |
cobS | ADN12807.1 | Cyan7822_0780 | Cyan7822_0781 | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | KEGG: cyh:Cyan8802_1195 hypothetical protein. | 0.567 |
cobS | guaA | Cyan7822_0780 | Cyan7822_3098 | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.413 |
cobS | tgt | Cyan7822_0780 | Cyan7822_0782 | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] | 0.461 |
guaA | ADN12189.1 | Cyan7822_3098 | Cyan7822_0138 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.485 |
guaA | cobS | Cyan7822_3098 | Cyan7822_0780 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.413 |
guaA | queF | Cyan7822_3098 | Cyan7822_1756 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.467 |
guaA | ribBA | Cyan7822_3098 | Cyan7822_5568 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.707 |