STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (449 aa)    
Predicted Functional Partners:
ADN16914.1
Manually curated; TIGRFAM: adenylosuccinate lyase; KEGG: cyh:Cyan8802_2587 adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
 0.996
ADN12751.1
KEGG: cyh:Cyan8802_0372 IMP dehydrogenase family protein; TIGRFAM: IMP dehydrogenase family protein; PFAM: IMP dehydrogenase/GMP reductase.
 
 
 0.992
purH
KEGG: cyh:Cyan8802_1344 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein; manually curated; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; SMART: AICARFT/IMPCHase bienzyme formylation region.
 
 0.983
pyrB
KEGG: cyh:Cyan8802_2958 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 
 0.947
argG
TIGRFAM: argininosuccinate synthase; KEGG: mar:MAE_02090 argininosuccinate synthase; PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.932
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
 
  
 0.926
ADN16317.1
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
     
 0.921
ADN14266.1
PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: bhy:BHWA1_01019 putative 5'-nucleotidase; Belongs to the 5'-nucleotidase family.
    
 0.916
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.914
ADN15680.1
KEGG: cyh:Cyan8802_2176 stationary-phase survival protein SurE; TIGRFAM: stationary-phase survival protein SurE; PFAM: Survival protein SurE.
    
 0.914
Your Current Organism:
Gloeothece verrucosa
NCBI taxonomy Id: 497965
Other names: Cyanothece sp. PCC 7822, G. verrucosa PCC 7822, Gloeothece verrucosa PCC 7822
Server load: low (26%) [HD]