STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypAHydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (114 aa)    
Predicted Functional Partners:
ADN13651.1
KEGG: ava:Ava_B0171 hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K.
 
 
 0.981
ADN13659.1
PFAM: nickel-dependent hydrogenase large subunit; KEGG: cyh:Cyan8802_2907 nickel-dependent hydrogenase large subunit.
 
 
 0.924
ADN14024.1
KEGG: syn:sll1079 hydrogenase expression/formation protein; HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K.
 
 
 0.905
ADN14987.1
KEGG: cyh:Cyan8802_0892 hydrogenase expression/formation protein HypD; TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein.
 
  
 0.827
ADN12667.1
KEGG: cyh:Cyan8802_2308 hydrogenase assembly chaperone HypC/HupF; TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC).
 
  
 0.817
ADN12668.1
KEGG: cyh:Cyan8802_2526 (NiFe) hydrogenase maturation protein HypF; TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: SUA5/yciO/yrdC domain; acylphosphatase; zinc finger HypF domain protein.
 
   
 0.816
ADN12671.1
KEGG: cyh:Cyan8802_2797 hydrogenase expression/formation protein HypE; TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein domain protein; AIR synthase related protein.
 
  
 0.816
ADN13658.1
PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: cyh:Cyan8802_2908 NADH ubiquinone oxidoreductase 20 kDa subunit.
 
  
 0.670
ADN13653.1
PFAM: NHL repeat containing protein; KEGG: cyh:Cyan8802_0109 NHL repeat containing protein.
 
     0.668
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.660
Your Current Organism:
Gloeothece verrucosa
NCBI taxonomy Id: 497965
Other names: Cyanothece sp. PCC 7822, G. verrucosa PCC 7822, Gloeothece verrucosa PCC 7822
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.