STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (369 aa)    
Predicted Functional Partners:
ADN14377.1
KEGG: ava:Ava_4890 anthranilate synthase; TIGRFAM: anthranilate synthase; glutamine amidotransferase of anthranilate synthase; PFAM: Chorismate binding-like; glutamine amidotransferase class-I; Anthranilate synthase component I domain protein.
 0.999
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
 
 0.999
ADN17432.1
KEGG: cyh:Cyan8802_2324 glutamine amidotransferase of anthranilate synthase; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I.
 
 0.999
trpF
PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: ava:Ava_2538 N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family.
 
 
 0.995
trpA-2
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.993
trpC-2
KEGG: ana:all0413 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
  
 0.993
trpC
KEGG: cyh:Cyan8802_2627 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
  
 0.988
trpB-3
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
  
 0.987
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.984
ADN16194.1
KEGG: cyh:Cyan8802_3230 para-aminobenzoate synthase component I; TIGRFAM: para-aminobenzoate synthase component I; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein; 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK.
 
 
 0.970
Your Current Organism:
Gloeothece verrucosa
NCBI taxonomy Id: 497965
Other names: Cyanothece sp. PCC 7822, G. verrucosa PCC 7822, Gloeothece verrucosa PCC 7822
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