node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
purC | purD | Cyan7822_4267 | Cyan7822_3237 | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: cyh:Cyan8802_0363 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | TIGRFAM: phosphoribosylamine/glycine ligase; KEGG: cyh:Cyan8802_4039 phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; Belongs to the GARS family. | 0.972 |
purC | purE | Cyan7822_4267 | Cyan7822_3129 | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: cyh:Cyan8802_0363 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.998 |
purC | purF | Cyan7822_4267 | Cyan7822_1866 | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: cyh:Cyan8802_0363 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.971 |
purC | purH | Cyan7822_4267 | Cyan7822_4968 | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: cyh:Cyan8802_0363 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | KEGG: cyh:Cyan8802_1344 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein; manually curated; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; SMART: AICARFT/IMPCHase bienzyme formylation region. | 0.977 |
purC | purK | Cyan7822_4267 | Cyan7822_1306 | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: cyh:Cyan8802_0363 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.990 |
purC | purL | Cyan7822_4267 | Cyan7822_1863 | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: cyh:Cyan8802_0363 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.952 |
purC | purM | Cyan7822_4267 | Cyan7822_5601 | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: cyh:Cyan8802_0363 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; KEGG: mar:MAE_44360 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. | 0.977 |
purC | purN | Cyan7822_4267 | Cyan7822_3511 | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: cyh:Cyan8802_0363 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.963 |
purC | purQ | Cyan7822_4267 | Cyan7822_5194 | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: cyh:Cyan8802_0363 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.961 |
purC | purS | Cyan7822_4267 | Cyan7822_5193 | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: cyh:Cyan8802_0363 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] | 0.941 |
purD | purC | Cyan7822_3237 | Cyan7822_4267 | TIGRFAM: phosphoribosylamine/glycine ligase; KEGG: cyh:Cyan8802_4039 phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; Belongs to the GARS family. | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: cyh:Cyan8802_0363 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | 0.972 |
purD | purE | Cyan7822_3237 | Cyan7822_3129 | TIGRFAM: phosphoribosylamine/glycine ligase; KEGG: cyh:Cyan8802_4039 phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; Belongs to the GARS family. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.997 |
purD | purF | Cyan7822_3237 | Cyan7822_1866 | TIGRFAM: phosphoribosylamine/glycine ligase; KEGG: cyh:Cyan8802_4039 phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; Belongs to the GARS family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.998 |
purD | purH | Cyan7822_3237 | Cyan7822_4968 | TIGRFAM: phosphoribosylamine/glycine ligase; KEGG: cyh:Cyan8802_4039 phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; Belongs to the GARS family. | KEGG: cyh:Cyan8802_1344 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein; manually curated; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; SMART: AICARFT/IMPCHase bienzyme formylation region. | 0.982 |
purD | purK | Cyan7822_3237 | Cyan7822_1306 | TIGRFAM: phosphoribosylamine/glycine ligase; KEGG: cyh:Cyan8802_4039 phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; Belongs to the GARS family. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.973 |
purD | purL | Cyan7822_3237 | Cyan7822_1863 | TIGRFAM: phosphoribosylamine/glycine ligase; KEGG: cyh:Cyan8802_4039 phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.969 |
purD | purM | Cyan7822_3237 | Cyan7822_5601 | TIGRFAM: phosphoribosylamine/glycine ligase; KEGG: cyh:Cyan8802_4039 phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; Belongs to the GARS family. | TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; KEGG: mar:MAE_44360 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. | 0.998 |
purD | purN | Cyan7822_3237 | Cyan7822_3511 | TIGRFAM: phosphoribosylamine/glycine ligase; KEGG: cyh:Cyan8802_4039 phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; Belongs to the GARS family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
purD | purQ | Cyan7822_3237 | Cyan7822_5194 | TIGRFAM: phosphoribosylamine/glycine ligase; KEGG: cyh:Cyan8802_4039 phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.995 |
purD | purS | Cyan7822_3237 | Cyan7822_5193 | TIGRFAM: phosphoribosylamine/glycine ligase; KEGG: cyh:Cyan8802_4039 phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] | 0.965 |