B9J08_001658 protein (Candida auris) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

B9J08_001658

Uncharacterized protein; Belongs to the peptidase M16 family. (1160 aa)

Predicted Functional Partners:

B9J08_000632

0.739

B9J08_003087

0.668

B9J08_004045

0.628

B9J08_000848

0.576

B9J08_001033

0.558

B9J08_000828

0.509

B9J08_004383

0.508

B9J08_003430

0.481

B9J08_005205

0.479

B9J08_005531

0.479

Your Current Organism:

Candida auris

NCBI taxonomy Id: 498019
Other names: B11220, CBS 10913, CBS10913, CDC B11220, Candida auris Satoh & Makimura, 2009, Candida sp. KM-143, DSM 21092, JCM 15448, JCM15448, [. auris, [Candida] auris

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B9J08_000632	B9J08_000828	A0A2H1A5H8	A0A2H1A640	Ubiquitin-40S ribosomal protein S27a.	Uncharacterized protein.	0.614
B9J08_000632	B9J08_001658	A0A2H1A5H8	A0A2H0ZY24	Ubiquitin-40S ribosomal protein S27a.	Uncharacterized protein; Belongs to the peptidase M16 family.	0.739
B9J08_000632	B9J08_003087	A0A2H1A5H8	A0A2H0ZS53	Ubiquitin-40S ribosomal protein S27a.	RRN7-type domain-containing protein.	0.999
B9J08_000828	B9J08_000632	A0A2H1A640	A0A2H1A5H8	Uncharacterized protein.	Ubiquitin-40S ribosomal protein S27a.	0.614
B9J08_000828	B9J08_000848	A0A2H1A640	A0A2H1A6Y5	Uncharacterized protein.	Uncharacterized protein.	0.608
B9J08_000828	B9J08_001658	A0A2H1A640	A0A2H0ZY24	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase M16 family.	0.509
B9J08_000848	B9J08_000828	A0A2H1A6Y5	A0A2H1A640	Uncharacterized protein.	Uncharacterized protein.	0.608
B9J08_000848	B9J08_001658	A0A2H1A6Y5	A0A2H0ZY24	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase M16 family.	0.576
B9J08_001033	B9J08_001658	A0A2H1A7L1	A0A2H0ZY24	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase M16 family.	0.558
B9J08_001033	B9J08_003430	A0A2H1A7L1	A0A2H0ZMG9	Uncharacterized protein.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.720
B9J08_001658	B9J08_000632	A0A2H0ZY24	A0A2H1A5H8	Uncharacterized protein; Belongs to the peptidase M16 family.	Ubiquitin-40S ribosomal protein S27a.	0.739
B9J08_001658	B9J08_000828	A0A2H0ZY24	A0A2H1A640	Uncharacterized protein; Belongs to the peptidase M16 family.	Uncharacterized protein.	0.509
B9J08_001658	B9J08_000848	A0A2H0ZY24	A0A2H1A6Y5	Uncharacterized protein; Belongs to the peptidase M16 family.	Uncharacterized protein.	0.576
B9J08_001658	B9J08_001033	A0A2H0ZY24	A0A2H1A7L1	Uncharacterized protein; Belongs to the peptidase M16 family.	Uncharacterized protein.	0.558
B9J08_001658	B9J08_003087	A0A2H0ZY24	A0A2H0ZS53	Uncharacterized protein; Belongs to the peptidase M16 family.	RRN7-type domain-containing protein.	0.668
B9J08_001658	B9J08_003430	A0A2H0ZY24	A0A2H0ZMG9	Uncharacterized protein; Belongs to the peptidase M16 family.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.481
B9J08_001658	B9J08_004045	A0A2H0ZY24	A0A2H0ZP64	Uncharacterized protein; Belongs to the peptidase M16 family.	Uncharacterized protein.	0.628
B9J08_001658	B9J08_004383	A0A2H0ZY24	A0A2H0ZIV3	Uncharacterized protein; Belongs to the peptidase M16 family.	PH domain-containing protein.	0.508
B9J08_001658	B9J08_005205	A0A2H0ZY24	A0A2H0ZD13	Uncharacterized protein; Belongs to the peptidase M16 family.	Uncharacterized protein.	0.479
B9J08_001658	B9J08_005531	A0A2H0ZY24	A0A2H0ZDX8	Uncharacterized protein; Belongs to the peptidase M16 family.	Uncharacterized protein.	0.479

page 1 of 2

Network Stats

number of nodes:

5

number of edges:

8

average node degree:

3.2

avg. local clustering coefficient:

0.867

expected number of edges:

4

PPI enrichment p-value:

0.052

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0140359

ABC-type transporter activity

3 of 18

2.01

1.16

0.0060

GO:0022804

Active transmembrane transporter activity

4 of 127

1.28

0.68

0.0290

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:7683

Type 1 protein exporter

3 of 6

2.48

1.9

0.00029

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02010

ABC transporters

3 of 39

1.67

1.1

0.0051

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-1369007

Mitochondrial ABC transporters

2 of 2

2.78

1.04

0.0132

MAP-9754706

Atorvastatin ADME

2 of 6

2.31

1.02

0.0132

MAP-159418

Recycling of bile acids and salts

2 of 5

2.39

1.02

0.0132

MAP-382556

ABC-family proteins mediated transport

3 of 33

1.74

0.94

0.0132

MAP-983170

Antigen Presentation: Folding, assembly and peptide loading of class I MHC

2 of 11

2.04

0.83

0.0284

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00664

ABC transporter transmembrane region

3 of 11

2.22

1.61

0.00088

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR039421

Type 1 protein exporter

3 of 7

2.42

1.64

0.00087

IPR036640

ABC transporter type 1, transmembrane domain superfamily

3 of 11

2.22

1.52

0.0013

IPR011527

ABC transporter type 1, transmembrane domain

3 of 11

2.22

1.52

0.0013

IPR017871

ABC transporter-like, conserved site

3 of 24

1.88

1.2

0.0042

IPR003439

ABC transporter-like, ATP-binding domain

3 of 26

1.85

1.19

0.0044

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00382

ATPases associated with a variety of cellular activities

4 of 70

1.54

1.28

0.0012

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