node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B9J08_000229 | B9J08_000650 | A0A2H1A7C7 | A0A2H1A5I7 | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.491 |
B9J08_000229 | B9J08_001702 | A0A2H1A7C7 | A0A2H0ZY98 | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | 0.505 |
B9J08_000229 | B9J08_001756 | A0A2H1A7C7 | A0A2H0ZZC8 | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. | 0.964 |
B9J08_000229 | B9J08_002652 | A0A2H1A7C7 | A0A2H0ZQV0 | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | Citrate synthase; Belongs to the citrate synthase family. | 0.517 |
B9J08_000229 | B9J08_003463 | A0A2H1A7C7 | A0A2H0ZMK5 | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | Histidine biosynthesis trifunctional protein. | 0.723 |
B9J08_000650 | B9J08_000229 | A0A2H1A5I7 | A0A2H1A7C7 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.491 |
B9J08_000650 | B9J08_000755 | A0A2H1A5I7 | A0A2H1A465 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Uncharacterized protein. | 0.509 |
B9J08_000650 | B9J08_000980 | A0A2H1A5I7 | A0A2H1A6I6 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.714 |
B9J08_000650 | B9J08_001702 | A0A2H1A5I7 | A0A2H0ZY98 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | 0.662 |
B9J08_000650 | B9J08_001756 | A0A2H1A5I7 | A0A2H0ZZC8 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. | 0.662 |
B9J08_000650 | B9J08_002652 | A0A2H1A5I7 | A0A2H0ZQV0 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Citrate synthase; Belongs to the citrate synthase family. | 0.886 |
B9J08_000650 | B9J08_003180 | A0A2H1A5I7 | A0A2H0ZLU3 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.714 |
B9J08_000755 | B9J08_000650 | A0A2H1A465 | A0A2H1A5I7 | Uncharacterized protein. | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.509 |
B9J08_000755 | B9J08_001702 | A0A2H1A465 | A0A2H0ZY98 | Uncharacterized protein. | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | 0.647 |
B9J08_000755 | B9J08_001756 | A0A2H1A465 | A0A2H0ZZC8 | Uncharacterized protein. | Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. | 0.984 |
B9J08_000755 | B9J08_002375 | A0A2H1A465 | A0A2H0ZX54 | Uncharacterized protein. | Uncharacterized protein. | 0.771 |
B9J08_000755 | B9J08_002652 | A0A2H1A465 | A0A2H0ZQV0 | Uncharacterized protein. | Citrate synthase; Belongs to the citrate synthase family. | 0.714 |
B9J08_000755 | B9J08_003463 | A0A2H1A465 | A0A2H0ZMK5 | Uncharacterized protein. | Histidine biosynthesis trifunctional protein. | 0.802 |
B9J08_000980 | B9J08_000650 | A0A2H1A6I6 | A0A2H1A5I7 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.714 |
B9J08_000980 | B9J08_001702 | A0A2H1A6I6 | A0A2H0ZY98 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | 0.757 |