node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CJA_1093 | clpB | CJA_1093 | CJA_3194 | 16 kDa heat shock protein A; Identified by match to protein family HMM PF00011; Belongs to the small heat shock protein (HSP20) family. | ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.662 |
CJA_1093 | dnaJ | CJA_1093 | CJA_3346 | 16 kDa heat shock protein A; Identified by match to protein family HMM PF00011; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.476 |
CJA_1093 | dnaK | CJA_1093 | CJA_3347 | 16 kDa heat shock protein A; Identified by match to protein family HMM PF00011; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.433 |
CJA_1093 | grpE | CJA_1093 | CJA_3348 | 16 kDa heat shock protein A; Identified by match to protein family HMM PF00011; Belongs to the small heat shock protein (HSP20) family. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.453 |
CJA_1093 | hscC | CJA_1093 | CJA_1169 | 16 kDa heat shock protein A; Identified by match to protein family HMM PF00011; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein hscC; Identified by match to protein family HMM PF00012; Belongs to the heat shock protein 70 family. | 0.433 |
CJA_1093 | hspC2 | CJA_1093 | CJA_1092 | 16 kDa heat shock protein A; Identified by match to protein family HMM PF00011; Belongs to the small heat shock protein (HSP20) family. | Small heat shock protein; Identified by match to protein family HMM PF00011; Belongs to the small heat shock protein (HSP20) family. | 0.771 |
CJA_1093 | htpG | CJA_1093 | CJA_1760 | 16 kDa heat shock protein A; Identified by match to protein family HMM PF00011; Belongs to the small heat shock protein (HSP20) family. | Putative Hsp90 protein; Molecular chaperone. Has ATPase activity. | 0.525 |
CJA_1652 | clpB | CJA_1652 | CJA_3194 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.714 |
CJA_1652 | clpP | CJA_1652 | CJA_2006 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.513 |
CJA_1652 | dnaK | CJA_1652 | CJA_3347 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.941 |
CJA_1652 | grpE | CJA_1652 | CJA_3348 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.888 |
CJA_1652 | hscC | CJA_1652 | CJA_1169 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | Chaperone protein hscC; Identified by match to protein family HMM PF00012; Belongs to the heat shock protein 70 family. | 0.941 |
CJA_1652 | htpG | CJA_1652 | CJA_1760 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | Putative Hsp90 protein; Molecular chaperone. Has ATPase activity. | 0.948 |
clpB | CJA_1093 | CJA_3194 | CJA_1093 | ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 16 kDa heat shock protein A; Identified by match to protein family HMM PF00011; Belongs to the small heat shock protein (HSP20) family. | 0.662 |
clpB | CJA_1652 | CJA_3194 | CJA_1652 | ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | DnaJ domain protein; Identified by match to protein family HMM PF00226. | 0.714 |
clpB | clpP | CJA_3194 | CJA_2006 | ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.916 |
clpB | clpS | CJA_3194 | CJA_2569 | ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease adaptor protein clpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.827 |
clpB | dnaJ | CJA_3194 | CJA_3346 | ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.734 |
clpB | dnaK | CJA_3194 | CJA_3347 | ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.920 |
clpB | grpE | CJA_3194 | CJA_3348 | ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.849 |