node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CJA_1466 | dnaJ | CJA_1466 | CJA_3346 | Cysteine desulfurase used in synthesis of Fe-S cluster (tRNA 4-thiouridine sulfurtransferase); Identified by match to protein family HMM PF00266. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.485 |
CJA_1466 | dnaK | CJA_1466 | CJA_3347 | Cysteine desulfurase used in synthesis of Fe-S cluster (tRNA 4-thiouridine sulfurtransferase); Identified by match to protein family HMM PF00266. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.776 |
CJA_1466 | grpE | CJA_1466 | CJA_3348 | Cysteine desulfurase used in synthesis of Fe-S cluster (tRNA 4-thiouridine sulfurtransferase); Identified by match to protein family HMM PF00266. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.605 |
CJA_1652 | clpA | CJA_1652 | CJA_2568 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | ATP-binding protease component ClpA; Identified by match to protein family HMM PF00004; match to protein family HMM PF02861; Belongs to the ClpA/ClpB family. | 0.714 |
CJA_1652 | clpB | CJA_1652 | CJA_3194 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.714 |
CJA_1652 | dnaK | CJA_1652 | CJA_3347 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.941 |
CJA_1652 | groES | CJA_1652 | CJA_2647 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | GroES protein; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.639 |
CJA_1652 | groL | CJA_1652 | CJA_2646 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.782 |
CJA_1652 | grpE | CJA_1652 | CJA_3348 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.888 |
CJA_1652 | htpG | CJA_1652 | CJA_1760 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | Putative Hsp90 protein; Molecular chaperone. Has ATPase activity. | 0.948 |
CJA_1652 | rplP | CJA_1652 | CJA_0706 | DnaJ domain protein; Identified by match to protein family HMM PF00226. | Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. | 0.668 |
clpA | CJA_1652 | CJA_2568 | CJA_1652 | ATP-binding protease component ClpA; Identified by match to protein family HMM PF00004; match to protein family HMM PF02861; Belongs to the ClpA/ClpB family. | DnaJ domain protein; Identified by match to protein family HMM PF00226. | 0.714 |
clpA | dnaJ | CJA_2568 | CJA_3346 | ATP-binding protease component ClpA; Identified by match to protein family HMM PF00004; match to protein family HMM PF02861; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.734 |
clpA | dnaK | CJA_2568 | CJA_3347 | ATP-binding protease component ClpA; Identified by match to protein family HMM PF00004; match to protein family HMM PF02861; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.920 |
clpA | groES | CJA_2568 | CJA_2647 | ATP-binding protease component ClpA; Identified by match to protein family HMM PF00004; match to protein family HMM PF02861; Belongs to the ClpA/ClpB family. | GroES protein; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.636 |
clpA | groL | CJA_2568 | CJA_2646 | ATP-binding protease component ClpA; Identified by match to protein family HMM PF00004; match to protein family HMM PF02861; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.615 |
clpA | grpE | CJA_2568 | CJA_3348 | ATP-binding protease component ClpA; Identified by match to protein family HMM PF00004; match to protein family HMM PF02861; Belongs to the ClpA/ClpB family. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.849 |
clpA | htpG | CJA_2568 | CJA_1760 | ATP-binding protease component ClpA; Identified by match to protein family HMM PF00004; match to protein family HMM PF02861; Belongs to the ClpA/ClpB family. | Putative Hsp90 protein; Molecular chaperone. Has ATPase activity. | 0.712 |
clpB | CJA_1652 | CJA_3194 | CJA_1652 | ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | DnaJ domain protein; Identified by match to protein family HMM PF00226. | 0.714 |
clpB | dnaJ | CJA_3194 | CJA_3346 | ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.734 |