node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFB02249.1 | SFB12763.1 | SAMN05660845_1361 | SAMN05660845_1769 | Tryptophan 2,3-dioxygenase apoenzyme. | Kynurenine formamidase. | 0.973 |
SFB02249.1 | SFB29707.1 | SAMN05660845_1361 | SAMN05660845_2485 | Tryptophan 2,3-dioxygenase apoenzyme. | ABC-type nitrate/sulfonate/bicarbonate transport system, substrate-binding protein. | 0.504 |
SFB02249.1 | kmo | SAMN05660845_1361 | SAMN05660845_1490 | Tryptophan 2,3-dioxygenase apoenzyme. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.570 |
SFB02249.1 | kynU | SAMN05660845_1361 | SAMN05660845_1487 | Tryptophan 2,3-dioxygenase apoenzyme. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.990 |
SFB02249.1 | nbaC | SAMN05660845_1361 | SAMN05660845_1712 | Tryptophan 2,3-dioxygenase apoenzyme. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.644 |
SFB11796.1 | SFB11812.1 | SAMN05660845_1713 | SAMN05660845_1714 | Hypothetical protein. | Hypothetical protein. | 0.705 |
SFB11796.1 | nbaC | SAMN05660845_1713 | SAMN05660845_1712 | Hypothetical protein. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.689 |
SFB11812.1 | SFB11796.1 | SAMN05660845_1714 | SAMN05660845_1713 | Hypothetical protein. | Hypothetical protein. | 0.705 |
SFB11812.1 | nbaC | SAMN05660845_1714 | SAMN05660845_1712 | Hypothetical protein. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.630 |
SFB12763.1 | SFB02249.1 | SAMN05660845_1769 | SAMN05660845_1361 | Kynurenine formamidase. | Tryptophan 2,3-dioxygenase apoenzyme. | 0.973 |
SFB12763.1 | kmo | SAMN05660845_1769 | SAMN05660845_1490 | Kynurenine formamidase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.920 |
SFB12763.1 | kynU | SAMN05660845_1769 | SAMN05660845_1487 | Kynurenine formamidase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.978 |
SFB12763.1 | nbaC | SAMN05660845_1769 | SAMN05660845_1712 | Kynurenine formamidase. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.481 |
SFB20678.1 | kmo | SAMN05660845_2024 | SAMN05660845_1490 | UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose reductase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.422 |
SFB20678.1 | nbaC | SAMN05660845_2024 | SAMN05660845_1712 | UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose reductase. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.455 |
SFB20678.1 | pgi | SAMN05660845_2024 | SAMN05660845_1722 | UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose reductase. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.428 |
SFB29707.1 | SFB02249.1 | SAMN05660845_2485 | SAMN05660845_1361 | ABC-type nitrate/sulfonate/bicarbonate transport system, substrate-binding protein. | Tryptophan 2,3-dioxygenase apoenzyme. | 0.504 |
SFB29707.1 | kmo | SAMN05660845_2485 | SAMN05660845_1490 | ABC-type nitrate/sulfonate/bicarbonate transport system, substrate-binding protein. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. | 0.575 |
SFB29707.1 | kynU | SAMN05660845_2485 | SAMN05660845_1487 | ABC-type nitrate/sulfonate/bicarbonate transport system, substrate-binding protein. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.481 |
SFB29707.1 | nbaC | SAMN05660845_2485 | SAMN05660845_1712 | ABC-type nitrate/sulfonate/bicarbonate transport system, substrate-binding protein. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.666 |