node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEF84415.1 | ddl | BSPA14S_0420 | BSPA14S_0196 | Putative sensory transduction histidine kinase; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518. | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.833 |
EEF84415.1 | gyrB | BSPA14S_0420 | BSPA14S_0443 | Putative sensory transduction histidine kinase; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.524 |
EEF84415.1 | mraY | BSPA14S_0420 | BSPA14S_0303 | Putative sensory transduction histidine kinase; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.477 |
EEF84415.1 | murA | BSPA14S_0420 | BSPA14S_0485 | Putative sensory transduction histidine kinase; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.828 |
EEF84415.1 | murB | BSPA14S_0420 | BSPA14S_0607 | Putative sensory transduction histidine kinase; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.715 |
EEF84655.1 | ddl | BSPA14S_0304 | BSPA14S_0196 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.998 |
EEF84655.1 | mraY | BSPA14S_0304 | BSPA14S_0303 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.999 |
EEF84655.1 | murA | BSPA14S_0304 | BSPA14S_0485 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.908 |
EEF84655.1 | murB | BSPA14S_0304 | BSPA14S_0607 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.897 |
EEF84655.1 | murC | BSPA14S_0304 | BSPA14S_0837 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.991 |
EEF84655.1 | murD | BSPA14S_0304 | BSPA14S_0596 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.994 |
EEF84655.1 | murE | BSPA14S_0304 | BSPA14S_0198 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.999 |
EEF84655.1 | murG | BSPA14S_0304 | BSPA14S_0787 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.995 |
ddl | EEF84415.1 | BSPA14S_0196 | BSPA14S_0420 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Putative sensory transduction histidine kinase; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518. | 0.833 |
ddl | EEF84655.1 | BSPA14S_0196 | BSPA14S_0304 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | 0.998 |
ddl | mraY | BSPA14S_0196 | BSPA14S_0303 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.883 |
ddl | murA | BSPA14S_0196 | BSPA14S_0485 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.874 |
ddl | murB | BSPA14S_0196 | BSPA14S_0607 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.952 |
ddl | murC | BSPA14S_0196 | BSPA14S_0837 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.991 |
ddl | murD | BSPA14S_0196 | BSPA14S_0596 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.962 |