STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpoDRNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (631 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.986
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
  
 0.970
rpoZ
DNA-directed RNA polymerase, omega subunit; Identified by match to protein family HMM TIGR00690.
   
 
 0.961
rpoC
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.955
rpoN
RNA polymerase sigma-54 factor; Identified by match to protein family HMM PF00309; match to protein family HMM PF04552; match to protein family HMM PF04963; match to protein family HMM TIGR02395.
   
 
 0.953
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.934
EEF84588.1
Ferric uptake regulation protein; Identified by match to protein family HMM PF01475; Belongs to the Fur family.
  
 
 0.933
EEF84812.1
Putative transcription factor; Identified by match to protein family HMM PF02559.
   
 
 0.904
EEF84415.1
Putative sensory transduction histidine kinase; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.
   
 
 0.881
csrA
Carbon storage regulator; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
      
 0.849
Your Current Organism:
Borreliella spielmanii
NCBI taxonomy Id: 498742
Other names: B. spielmanii A14S, Borrelia spielmanii A14S, Borreliella spielmanii A14S
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.