node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HM1_0345 | sdhA | HM1_0345 | HM1_0372 | acetyl-CoA hydrolase, putative. | This HMM represents the succinate dehydrogenase flavoprotein subunit as found in the low-GC Gram-positive bacteria and a few other lineages. This enzyme may act in a complete or partial TCA cycle, or act in the opposite direction as fumarate reductase. | 0.911 |
HM1_0345 | sdhB | HM1_0345 | HM1_0373 | acetyl-CoA hydrolase, putative. | Succinate dehydrogenase/fumarate reductase iron-sulfur protein. | 0.914 |
HM1_0345 | sdhC | HM1_0345 | HM1_0371 | acetyl-CoA hydrolase, putative. | Succinate dehydrogenase (cytochrome b558 subunit). | 0.904 |
HM1_0345 | sucC | HM1_0345 | HM1_0374 | acetyl-CoA hydrolase, putative. | Succinyl-coa synthase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.928 |
HM1_0345 | sucD | HM1_0345 | HM1_0375 | acetyl-CoA hydrolase, putative. | Succinyl-coa synthetase alpha chain 2; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.926 |
HM1_1028 | HM1_2651 | HM1_1028 | HM1_2651 | NADH dehydrogenase conserved domain protein, nuoe and nuof. | Uncharacterized protein ygfk; May contain a pyridine nucleotide-disulfide oxidoreductase domain and a 4Fe-4S binding domain. | 0.820 |
HM1_1028 | nuoF | HM1_1028 | HM1_1744 | NADH dehydrogenase conserved domain protein, nuoe and nuof. | Proton-translocating NADH-ubiquinone oxidoreductase, chain f. | 0.999 |
HM1_1028 | sdhA | HM1_1028 | HM1_0372 | NADH dehydrogenase conserved domain protein, nuoe and nuof. | This HMM represents the succinate dehydrogenase flavoprotein subunit as found in the low-GC Gram-positive bacteria and a few other lineages. This enzyme may act in a complete or partial TCA cycle, or act in the opposite direction as fumarate reductase. | 0.981 |
HM1_1028 | sdhB | HM1_1028 | HM1_0373 | NADH dehydrogenase conserved domain protein, nuoe and nuof. | Succinate dehydrogenase/fumarate reductase iron-sulfur protein. | 0.983 |
HM1_1028 | sdhC | HM1_1028 | HM1_0371 | NADH dehydrogenase conserved domain protein, nuoe and nuof. | Succinate dehydrogenase (cytochrome b558 subunit). | 0.956 |
HM1_1028 | sucC | HM1_1028 | HM1_0374 | NADH dehydrogenase conserved domain protein, nuoe and nuof. | Succinyl-coa synthase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.952 |
HM1_1028 | sucD | HM1_1028 | HM1_0375 | NADH dehydrogenase conserved domain protein, nuoe and nuof. | Succinyl-coa synthetase alpha chain 2; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.958 |
HM1_2651 | HM1_1028 | HM1_2651 | HM1_1028 | Uncharacterized protein ygfk; May contain a pyridine nucleotide-disulfide oxidoreductase domain and a 4Fe-4S binding domain. | NADH dehydrogenase conserved domain protein, nuoe and nuof. | 0.820 |
HM1_2651 | nuoF | HM1_2651 | HM1_1744 | Uncharacterized protein ygfk; May contain a pyridine nucleotide-disulfide oxidoreductase domain and a 4Fe-4S binding domain. | Proton-translocating NADH-ubiquinone oxidoreductase, chain f. | 0.685 |
HM1_2651 | sdhA | HM1_2651 | HM1_0372 | Uncharacterized protein ygfk; May contain a pyridine nucleotide-disulfide oxidoreductase domain and a 4Fe-4S binding domain. | This HMM represents the succinate dehydrogenase flavoprotein subunit as found in the low-GC Gram-positive bacteria and a few other lineages. This enzyme may act in a complete or partial TCA cycle, or act in the opposite direction as fumarate reductase. | 0.968 |
HM1_2651 | sdhB | HM1_2651 | HM1_0373 | Uncharacterized protein ygfk; May contain a pyridine nucleotide-disulfide oxidoreductase domain and a 4Fe-4S binding domain. | Succinate dehydrogenase/fumarate reductase iron-sulfur protein. | 0.461 |
HM1_2651 | sdhC | HM1_2651 | HM1_0371 | Uncharacterized protein ygfk; May contain a pyridine nucleotide-disulfide oxidoreductase domain and a 4Fe-4S binding domain. | Succinate dehydrogenase (cytochrome b558 subunit). | 0.655 |
HM1_2651 | sucD | HM1_2651 | HM1_0375 | Uncharacterized protein ygfk; May contain a pyridine nucleotide-disulfide oxidoreductase domain and a 4Fe-4S binding domain. | Succinyl-coa synthetase alpha chain 2; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.416 |
fumB | sdhA | HM1_0464 | HM1_0372 | Fumarate hydratase, beta subunit. | This HMM represents the succinate dehydrogenase flavoprotein subunit as found in the low-GC Gram-positive bacteria and a few other lineages. This enzyme may act in a complete or partial TCA cycle, or act in the opposite direction as fumarate reductase. | 0.967 |
fumB | sdhB | HM1_0464 | HM1_0373 | Fumarate hydratase, beta subunit. | Succinate dehydrogenase/fumarate reductase iron-sulfur protein. | 0.956 |