Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
HM1_1069Methicillin resistance protein, putative. (356 aa)    
Predicted Functional Partners:
HM1_1258
Conserved hypothetical protein; Member of the DegT/DnrJ/EryC1/StrS aminotransferase PFAM, PF01041, and also Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis COG, COG0399; Belongs to the DegT/DnrJ/EryC1 family.
      0.628
alr
Alanine racemase, putative; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
     
 0.585
mviN-2
Integral membrane protein mvin; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
 
     0.567
HM1_2727
Peptidoglycan glycosyltransferase.
  
   
 0.539
pyrG
Ctp synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
       0.510
HM1_1093
Conserved hypothetical protein.
  
     0.499
sppA
Signal peptide peptidase sppa, 36k type.
       0.483
HM1_1799
Duf710 protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
  
     0.443
mviN
Integral membrane protein mvin; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
 
     0.432
HM1_0452
Dolichyl-phosphate-mannose-protein mannosyltransferase, putative.
 
     0.404
Your Current Organism:
Heliobacterium modesticaldum
NCBI taxonomy Id: 498761
Other names: H. modesticaldum Ice1, Heliobacterium modesticaldum Ice1, Heliobacterium modesticaldum str. Ice1, Heliobacterium modesticaldum strain Ice1
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