STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HM1_1307Conserved hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (457 aa)    
Predicted Functional Partners:
HM1_1306
ATP-binding protein; Displays ATPase and GTPase activities.
  
  
 0.967
whiA
Conserved hypothetical protein; Involved in cell division and chromosome segregation.
  
  
 0.950
HM1_1309
Acetyltransferase; May contain bacterial transferase hexapeptide (three repeats).
       0.735
rpoN
RNA polymerase sigma-54 factor.
       0.688
HM1_2137
Protein serine/threonine phosphatase, putative.
   
  
 0.620
HM1_2540
Cell envelope-related transcriptional attenuator, putative.
  
     0.587
topA
DNA topoisomerase i; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
   0.503
HM1_1304
Alpha amylase catalytic region, putative.
       0.499
malQ
4-alpha-glucanotransferase.
       0.499
spoVD
Stage v sporulation protein d; Also matches penicillin binding protein transpeptidase domain, PF00905, and penicillin-binding protein dimerisation domain PFAM, PF03717.
 
   
 0.495
Your Current Organism:
Heliobacterium modesticaldum
NCBI taxonomy Id: 498761
Other names: H. modesticaldum Ice1, Heliobacterium modesticaldum Ice1, Heliobacterium modesticaldum str. Ice1, Heliobacterium modesticaldum strain Ice1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.