STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HM1_1586Conserved domain protein; Similar to stage II sporulation protein E, PF07228, and matches COG2208, serine phosphatase RsbU, regulator of sigma subunit. (639 aa)    
Predicted Functional Partners:
HM1_0638
Sensor histidine kinase.
 
 
 0.962
HM1_0196
Sensory transduction histidine kinase, putative; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.941
HM1_0141
Two-component system sensor protein, putative.
 
 
 0.940
HM1_1587
Ggdef domain protein, putative.
 
  
 0.937
HM1_1611
Sensor histidine kinase, putative.
 
 
 0.937
HM1_1911
Signal transduction histidine kinase.
 
 
 0.935
HM1_1584
Conserved hypothetical protein.
 
  
 0.933
HM1_1585
Conserved hypothetical protein.
 
    0.933
HM1_1906
Response regulator.
 
 
 0.926
HM1_2633
Two-component system sensor protein.
 
 
 0.919
Your Current Organism:
Heliobacterium modesticaldum
NCBI taxonomy Id: 498761
Other names: H. modesticaldum Ice1, Heliobacterium modesticaldum Ice1, Heliobacterium modesticaldum str. Ice1, Heliobacterium modesticaldum strain Ice1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.