STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HM1_1767Hypothetical protein. (924 aa)    
Predicted Functional Partners:
HM1_2428
Conserved hypothetical protein; Similar to membrane protein.
  
     0.608
lonB
ATP-dependent protease lonb, putative.
  
     0.603
HM1_2001
Conserved domain protein; Similar to small, acid soluble spore protein.
  
     0.587
HM1_2100
Conserved hypothetical protein.
  
     0.576
HM1_2352
Hypothetical protein.
  
     0.554
HM1_3123
Hypothetical protein.
  
     0.551
disA
DNA-binding protein, putative; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
  
     0.492
cotS
Putative spore coat protein s, putative.
  
     0.469
HM1_0338
Hypothetical protein.
  
     0.451
HM1_0331
Hypothetical protein.
  
     0.434
Your Current Organism:
Heliobacterium modesticaldum
NCBI taxonomy Id: 498761
Other names: H. modesticaldum Ice1, Heliobacterium modesticaldum Ice1, Heliobacterium modesticaldum str. Ice1, Heliobacterium modesticaldum strain Ice1
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