STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HM1_1970Transcriptional regulator, putative. (161 aa)    
Predicted Functional Partners:
HM1_1969
Radical sam; Member of COG0535, predicted Fe-S oxidoreductases.
  
 0.994
HM1_1971
Heme biosynthesis protein.
    
0.981
HM1_1967
Elongator protein 3/miab/nifb, putative.
  
 0.911
cobA
Uroporphyrinogen iii synthase/methyltransferase; C-terminal region containing conserved CysG domain and N-ternimal region containing HemD domain protein.
 
  
 0.660
hemB
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
     
 0.559
hemL
Glutamate-1-semialdehyde-2,1-aminomutase heml; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
     
 0.550
gltB
Glutamate synthase [nadph] large chain.
     
 0.538
HM1_1963
Siroheme synthase, n-terminal.
 
     0.506
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
     
 0.418
Your Current Organism:
Heliobacterium modesticaldum
NCBI taxonomy Id: 498761
Other names: H. modesticaldum Ice1, Heliobacterium modesticaldum Ice1, Heliobacterium modesticaldum str. Ice1, Heliobacterium modesticaldum strain Ice1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.