Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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fdhDFormate dehydrogenase family accessory protein fdhd; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (317 aa)    
Predicted Functional Partners:
mobA
Molybdopterin-guanine dinucleotide biosynthesis protein a; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
 
 
 0.990
mobB
Molybdopterin-guanine dinucleotide biosynthesis protein b.
    0.922
fdhA-2
Formate dehydrogenase, alpha subunit.
 
 
 0.849
fdhA
Formate dehydrogenase, alpha subunit.
 
 
 0.840
moaA
Molybdenum cofactor biosynthesis protein a; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
  
 0.831
nifS-2
Cysteine desulfurase family protein; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
 
 0.780
HM1_2676
Molybdenum cofactor biosynthesis protein, putative; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
   
 0.685
HM1_1028
NADH dehydrogenase conserved domain protein, nuoe and nuof.
  
  
 0.683
nuoF
Proton-translocating NADH-ubiquinone oxidoreductase, chain f.
  
  
 0.646
HM1_0334
Abc transporter, substrate-binding protein; Putative tungstate transporter.
 
     0.552
Your Current Organism:
Heliobacterium modesticaldum
NCBI taxonomy Id: 498761
Other names: H. modesticaldum Ice1, Heliobacterium modesticaldum Ice1, Heliobacterium modesticaldum str. Ice1, Heliobacterium modesticaldum strain Ice1
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