STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HM1_2012Nad/fad binding oxidoreductase. (334 aa)    
Predicted Functional Partners:
HM1_2011
4fe-4S ferredoxin, iron-sulfur binding protein, putative.
   
 0.995
HM1_2651
Uncharacterized protein ygfk; May contain a pyridine nucleotide-disulfide oxidoreductase domain and a 4Fe-4S binding domain.
  
 
 0.987
pyrD
Dihydroorotate dehydrogenase, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
 
 
 0.971
mvhD
Methyl-viologen-reducing hydrogenase domain protein, subunit d, putative.
 
 
 0.917
HM1_2010
4fe-4S ferredoxin, iron-sulfur binding protein, putative.
 
   0.902
hdrA
Heterodisulfide reductase, subunit a.
 
  
 0.865
HM1_2006
4fe-4S ferredoxin, iron-sulfur binding protein, putative.
 
   
 0.820
HM1_2007
Heterodisulfide reductase, putative.
 
  
 0.818
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
  
 0.812
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.809
Your Current Organism:
Heliobacterium modesticaldum
NCBI taxonomy Id: 498761
Other names: H. modesticaldum Ice1, Heliobacterium modesticaldum Ice1, Heliobacterium modesticaldum str. Ice1, Heliobacterium modesticaldum strain Ice1
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