Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HM1_2017GTPase subunit of restriction endonuclease, putative. (492 aa)    
Predicted Functional Partners:
HM1_2016
Hypothetical protein.
  
 
 0.981
HM1_2018
Cyclic nucleotide-binding transcriptional regulator, putative.
       0.678
HM1_2023
Methylase of chemotaxis methyl-accepting protein, putative.
 
     0.448
HM1_0633
Type i restriction modification DNA specificity domain.
  
  
 0.433
HM1_3076
Type i restriction modification DNA specificity domain protein.
  
  
 0.420
HM1_2019
Hypothetical protein.
       0.409
dcm
DNA-cytosine methyltransferase.
     
 0.407
Your Current Organism:
Heliobacterium modesticaldum
NCBI taxonomy Id: 498761
Other names: H. modesticaldum Ice1, Heliobacterium modesticaldum Ice1, Heliobacterium modesticaldum str. Ice1, Heliobacterium modesticaldum strain Ice1
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