STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HM1_2459Cbs domain protein, putative. (200 aa)    
Predicted Functional Partners:
HM1_2460
Conserved hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
 
  
 0.927
ppdK
Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
 
  
 0.751
adhE
Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.634
fabG
3-oxoacyl-[acyl-carrier-protein] reductase.
  
  
 0.611
fabG-2
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 0.611
glyS
glycyl-tRNA synthetase, beta subunit.
  
    0.597
HM1_0848
Conserved hypothetical protein; Similar to GGDEF domain.
  
  
 0.563
rpiB
Ribose 5-phosphate isomerase b.
  
  
 0.555
guaA
Gmp synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.545
tal
Transaldolase, putative; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
  
 0.545
Your Current Organism:
Heliobacterium modesticaldum
NCBI taxonomy Id: 498761
Other names: H. modesticaldum Ice1, Heliobacterium modesticaldum Ice1, Heliobacterium modesticaldum str. Ice1, Heliobacterium modesticaldum strain Ice1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.