STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HM1_2501Hypothetical protein. (272 aa)    
Predicted Functional Partners:
HM1_1028
NADH dehydrogenase conserved domain protein, nuoe and nuof.
   
 
 0.931
HM1_0615
Hypothetical protein.
  
 0.902
HM1_2411
Hypothetical protein.
  
 0.902
dnaK
Chaperone protein dnak; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.902
grpE
Co-chaperone grpe; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
  
 
 0.895
htpG
Heat shock protein htpg; Molecular chaperone. Has ATPase activity.
  
 0.866
HM1_1330
Conserved hypothetical protein; Similar to Chaperone protein htpG (Heat shock protein htpG).
  
 0.866
HM1_0822
Fad-dependent pyridine nucleotide-disulfide oxidoreductase, putative.
  
 
 0.825
HM1_1475
Transcriptional regulator, marr family.
  
 
 0.818
HM1_1958
Superoxide dismutase (fe).
  
 
 0.806
Your Current Organism:
Heliobacterium modesticaldum
NCBI taxonomy Id: 498761
Other names: H. modesticaldum Ice1, Heliobacterium modesticaldum Ice1, Heliobacterium modesticaldum str. Ice1, Heliobacterium modesticaldum strain Ice1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.