STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HM1_2600Subtilin family serine protease, putative; Belongs to the peptidase S8 family. (310 aa)    
Predicted Functional Partners:
HM1_0787
Subtilase, putative.
  
    0.769
HM1_3017
Conserved hypothetical protein.
 
 
 0.596
HM1_2599
Hypothetical protein.
       0.508
HM1_2122
Calcium-translocating p-type ATPase.
  
 
 0.426
HM1_0578
Conserved hypothetical protein; Member of the S-layer homology domain, PF00395, and the PKD domain, PF00801.
  
 
 0.410
HM1_0991
Hypothetical protein.
  
 
 0.410
HM1_1121
Amylopullulanase domain protein, putative.
 
 
 0.410
HM1_1856
Conserved hypothetical protein; Member of S-layer homology domain, PF00395.
  
 
 0.410
secY
Preprotein translocase, secy subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
    
 
 0.403
Your Current Organism:
Heliobacterium modesticaldum
NCBI taxonomy Id: 498761
Other names: H. modesticaldum Ice1, Heliobacterium modesticaldum Ice1, Heliobacterium modesticaldum str. Ice1, Heliobacterium modesticaldum strain Ice1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.