STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TO73_0502Hypothetical protein. (737 aa)    
Predicted Functional Partners:
TO73_0503
ATP-dependent DNA helicase UvrD/PcrA.
  
 0.999
TO73_0500
Hypothetical protein.
       0.704
TO73_0501
Hypothetical protein.
       0.704
TO73_0499
Sensor histidine kinase.
  
    0.670
TO73_0496
Protein phosphatase 2C.
       0.668
TO73_0497
Serine/threonine protein kinase.
       0.668
TO73_0498
Putative two-component response regulator.
       0.668
TO73_2081
Osmotically inducible protein C.
   
    0.511
TO73_0495
Hypothetical protein.
       0.491
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
     
 0.421
Your Current Organism:
Thermus aquaticus
NCBI taxonomy Id: 498848
Other names: T. aquaticus Y51MC23, Thermus aquaticus Y51MC23, Thermus aquaticus str. Y51MC23, Thermus aquaticus strain Y51MC23
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.