node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
TO73_1131 | TO73_1132 | TO73_1131 | TO73_1132 | Aminodeoxychorismate lyase. | Para-aminobenzoate synthase, amidotransferase component. | 0.943 |
TO73_1132 | TO73_1131 | TO73_1132 | TO73_1131 | Para-aminobenzoate synthase, amidotransferase component. | Aminodeoxychorismate lyase. | 0.943 |
TO73_1132 | TO73_2028 | TO73_1132 | TO73_2028 | Para-aminobenzoate synthase, amidotransferase component. | Anthranilate synthase, amidotransferase component. | 0.920 |
TO73_1132 | TO73_2174 | TO73_1132 | TO73_2174 | Para-aminobenzoate synthase, amidotransferase component. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.826 |
TO73_1132 | aroE | TO73_1132 | TO73_0711 | Para-aminobenzoate synthase, amidotransferase component. | Shikimate 5-dehydrogenase I alpha; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.765 |
TO73_1132 | trpA | TO73_1132 | TO73_1736 | Para-aminobenzoate synthase, amidotransferase component. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.999 |
TO73_1132 | trpB | TO73_1132 | TO73_1737 | Para-aminobenzoate synthase, amidotransferase component. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.999 |
TO73_1132 | trpC | TO73_1132 | TO73_1290 | Para-aminobenzoate synthase, amidotransferase component. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.999 |
TO73_1132 | trpD | TO73_1132 | TO73_2027 | Para-aminobenzoate synthase, amidotransferase component. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
TO73_1132 | trpE | TO73_1132 | TO73_2029 | Para-aminobenzoate synthase, amidotransferase component. | Anthranilate synthase, aminase component; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high c [...] | 0.923 |
TO73_1132 | trpF | TO73_1132 | TO73_0471 | Para-aminobenzoate synthase, amidotransferase component. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.999 |
TO73_2028 | TO73_1132 | TO73_2028 | TO73_1132 | Anthranilate synthase, amidotransferase component. | Para-aminobenzoate synthase, amidotransferase component. | 0.920 |
TO73_2028 | TO73_2174 | TO73_2028 | TO73_2174 | Anthranilate synthase, amidotransferase component. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.526 |
TO73_2028 | aroE | TO73_2028 | TO73_0711 | Anthranilate synthase, amidotransferase component. | Shikimate 5-dehydrogenase I alpha; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.519 |
TO73_2028 | trpA | TO73_2028 | TO73_1736 | Anthranilate synthase, amidotransferase component. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.910 |
TO73_2028 | trpB | TO73_2028 | TO73_1737 | Anthranilate synthase, amidotransferase component. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.859 |
TO73_2028 | trpC | TO73_2028 | TO73_1290 | Anthranilate synthase, amidotransferase component. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.993 |
TO73_2028 | trpD | TO73_2028 | TO73_2027 | Anthranilate synthase, amidotransferase component. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
TO73_2028 | trpE | TO73_2028 | TO73_2029 | Anthranilate synthase, amidotransferase component. | Anthranilate synthase, aminase component; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high c [...] | 0.999 |
TO73_2028 | trpF | TO73_2028 | TO73_0471 | Anthranilate synthase, amidotransferase component. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.952 |