Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
TO73_1237Sensor histidine kinase. (559 aa)    
Predicted Functional Partners:
TO73_1236
DNA-binding response regulator, LuxR family.
 
 
 0.972
TO73_0589
DNA-binding response regulator, LuxR family.
 
 
 0.880
TO73_1115
DNA-binding response regulator.
 
 
 0.873
TO73_1238
Phosphonate ABC transporter phosphate-binding periplasmic component; TC 3.A.1.9.1.
     
 0.773
TO73_1239
Molybdopterin oxidoreductase iron-sulfur binding subunit.
 
     0.608
TO73_1240
Tetrathionate reductase subunit A; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
       0.515
TO73_1713
Diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s).
 
   
 0.415
Your Current Organism:
Thermus aquaticus
NCBI taxonomy Id: 498848
Other names: T. aquaticus Y51MC23, Thermus aquaticus Y51MC23, Thermus aquaticus str. Y51MC23, Thermus aquaticus strain Y51MC23
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