STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TO73_1471Prephenate and/or arogenate dehydrogenase. (359 aa)    
Predicted Functional Partners:
aroA
5-Enolpyruvylshikimate-3-phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
 0.985
TO73_2053
Chorismate mutase I / 2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase I beta.
 
 0.985
TO73_0861
L-threonine 3-O-phosphate decarboxylase.
  
 
 0.968
hisC
Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.968
pheA
Prephenate dehydratase.
 
 0.957
TO73_1081
Chorismate mutase II; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
 
 
  0.936
TO73_2338
Biosynthetic Aromatic amino acid aminotransferase alpha / aspartate aminotransferase.
  
 
 0.922
TO73_1470
2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I beta.
 
  
 0.885
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.867
cmk
Cytidylate kinase.
 
  
 0.784
Your Current Organism:
Thermus aquaticus
NCBI taxonomy Id: 498848
Other names: T. aquaticus Y51MC23, Thermus aquaticus Y51MC23, Thermus aquaticus str. Y51MC23, Thermus aquaticus strain Y51MC23
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