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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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TO73_2002Citrate synthase (si); Belongs to the citrate synthase family. (377 aa)    
Predicted Functional Partners:
TO73_1591
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 0.999
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.986
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.978
TO73_0137
Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex.
  
 0.971
TO73_2200
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.971
TO73_0627
Malate synthase; Belongs to the malate synthase family.
   
 0.962
TO73_1447
Acetyl-coenzyme A synthetase; Overlaps another CDS with the same name.
  
 0.959
sucC
succinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.954
TO73_0154
2-oxoglutarate dehydrogenase E1 component.
  
 0.945
TO73_2162
2-oxoglutarate oxidoreductase, alpha subunit.
     
 0.939
Your Current Organism:
Thermus aquaticus
NCBI taxonomy Id: 498848
Other names: T. aquaticus Y51MC23, Thermus aquaticus Y51MC23, Thermus aquaticus str. Y51MC23, Thermus aquaticus strain Y51MC23
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