STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWV95958.1Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)    
Predicted Functional Partners:
ychF
GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
       0.848
KWV95957.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.669
ppnK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
   
 
  0.658
ndk
Phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
 0.634
KWV95955.1
Acyl dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.632
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
    
  0.619
KWV95960.1
Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.595
KWV93676.1
Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.593
KWV95035.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.585
KWV94064.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.558
Your Current Organism:
Erythrobacter sp. AP23
NCBI taxonomy Id: 499656
Other names: E. sp. AP23
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.